JMJD1B

Lysine (K)-specific demethylase 3B
Identifiers
Symbols	KDM3B; 5qNCA; C5orf7; JMJD1B; NET22
External IDs	OMIM: 609373 MGI: 1923356 HomoloGene: 41145 GeneCards: KDM3B Gene
Gene Ontology Molecular function • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen • metal ion binding Cellular component • nucleus • nucleolus Biological process • transcription, DNA-dependent • regulation of transcription, DNA-dependent • chromatin modification Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51780	277250
Ensembl	ENSG00000120733	ENSMUSG00000038773
UniProt	Q7LBC6	B9EKS2
RefSeq (mRNA)	NM_016604	NM_001081256
RefSeq (protein)	NP_057688	NP_001074725
Location (UCSC)	Chr 5: 137.69 – 137.77 Mb	Chr 18: 34.78 – 34.84 Mb
PubMed search	[1]	[2]

Lysine-specific demethylase 3B is an enzyme that in humans is encoded by the KDM3B gene.

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954. 
• Kikuno R, Nagase T, Ishikawa K, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851. 
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800. 
• Lai F, Godley LA, Fernald AA, et al. (2001). "cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins.". Genomics 70 (1): 123–30. doi:10.1006/geno.2000.6345. PMID 11087669. 
• Lai F, Godley LA, Joslin J, et al. (2001). "Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q).". Genomics 71 (2): 235–45. doi:10.1006/geno.2000.6414. PMID 11161817. 
• Hu Z, Gomes I, Horrigan SK, et al. (2001). "A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.". Oncogene 20 (47): 6946–54. doi:10.1038/sj.onc.1204850. PMID 11687974. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. 
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. 
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. 
• Yamane K, Toumazou C, Tsukada Y, et al. (2006). "JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.". Cell 125 (3): 483–95. doi:10.1016/j.cell.2006.03.027. PMID 16603237. 
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 

External links

• JMJD1B protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.