IRX6
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| Iroquois homeobox 6 | ||||||||
|---|---|---|---|---|---|---|---|---|
| Identifiers | ||||||||
| Symbols | IRX6; IRX-3; IRX7; IRXB3 | |||||||
| External IDs | OMIM: 606196 MGI: 1927642 HomoloGene: 41481 GeneCards: IRX6 Gene | |||||||
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| Orthologs | ||||||||
| Species | Human | Mouse | ||||||
| Entrez | 79190 | 64379 | ||||||
| Ensembl | ENSG00000159387 | ENSMUSG00000031738 | ||||||
| UniProt | P78412 | Q9ER75 | ||||||
| RefSeq (mRNA) | NM_024335 | NM_022428 | ||||||
| RefSeq (protein) | NP_077311 | NP_071873 | ||||||
| Location (UCSC) | Chr 16: 55.36 – 55.36 Mb |
Chr 8: 92.67 – 92.68 Mb |
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| PubMed search | [1] | [2] | ||||||
Iroquois-class homeodomain protein IRX-6, also known as Iroquois homeobox protein 6, is a protein that in humans is encoded by the IRX6 gene.[1][2]
[edit] Function
IRX6 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[1]
[edit] References
- ^ a b "Entrez Gene: iroquois homeobox 6". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79190.
- ^ Ogura K, Matsumoto K, Kuroiwa A, Isobe T, Otoguro T, Jurecic V, Baldini A, Matsuda Y, Ogura T (2001). "Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes". Cytogenet. Cell Genet. 92 (3–4): 320–5. doi:10.1159/000056921. PMID 11435706.
[edit] Further reading
- Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Lewis MT, Ross S, Strickland PA, et al. (1999). "Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast". Cell Tissue Res. 296 (3): 549–54. doi:10.1007/s004410051316. PMID 10370142.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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