NKX6-2

NK6 homeobox 2
Identifiers
Symbols	NKX6-2; GTX; NKX6.2; NKX6B
External IDs	OMIM: 605955 MGI: 1352738 HomoloGene: 18580 GeneCards: NKX6-2 Gene
Gene Ontology
Molecular function	• transcription regulatory region sequence-specific DNA binding; • sequence-specific DNA binding transcription factor activity;
Cellular component	• nucleus;
Biological process	• negative regulation of transcription from RNA polymerase II promoter; • regulation of transcription, DNA-dependent; • negative regulation of cell fate commitment; • positive regulation of cell fate commitment; • regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification; • regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; • central nervous system myelination; • endocrine pancreas development; • negative regulation of glial cell differentiation; • positive regulation of glial cell differentiation; • neuromuscular process controlling balance;
	Sources: Amigo / QuickGO
Orthologs
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Homeobox protein Nkx-6.2 is a protein that in humans is encoded by the NKX6-2 gene.^[1]^[2]

[edit] References

^ Lee SH, Davison JA, Vidal SM, Belouchi A (February 2001). "Cloning, expression and chromosomal location of NKX6B TO 10Q26, a region frequently deleted in brain tumors". Mamm. Genome 12 (2): 157–62. doi:10.1007/s003350010247. PMID 11210186.
^ "Entrez Gene: NK6 homeobox 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84504.

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.