GTF3A
From Wikipedia, the free encyclopedia
| General transcription factor IIIA | ||||||||
|---|---|---|---|---|---|---|---|---|
| Identifiers | ||||||||
| Symbols | GTF3A; AP2; TFIIIA | |||||||
| External IDs | OMIM: 600860 HomoloGene: 55630 GeneCards: GTF3A Gene | |||||||
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| Orthologs | ||||||||
| Species | Human | Mouse | ||||||
| Entrez | 2971 | 66596 | ||||||
| Ensembl | ENSG00000122034 | ENSMUSG00000016503 | ||||||
| UniProt | Q92664 | Q8VHT7 | ||||||
| RefSeq (mRNA) | NM_002097 | NM_025652 | ||||||
| RefSeq (protein) | NP_002088 | NP_079928 | ||||||
| Location (UCSC) | Chr 13: 28 – 28.01 Mb |
Chr 5: 146.95 – 146.96 Mb |
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| PubMed search | [1] | [2] | ||||||
Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene.[1][2]
[edit] References
- ^ Arakawa H, Nagase H, Hayashi N, Ogawa M, Nagata M, Fujiwara T, Takahashi E, Shin S, Nakamura Y (Jul 1995). "Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA". Cytogenet Cell Genet 70 (3–4): 235–8. doi:10.1159/000134041. PMID 7789179.
- ^ "Entrez Gene: GTF3A general transcription factor IIIA". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2971.
[edit] Further reading
- Murphy JE, Keen JH (1992). "Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia". J. Biol. Chem. 267 (15): 10850–5. PMID 1587861.
- Seifart KH, Wang L, Waldschmidt R, et al. (1989). "Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNA". J. Biol. Chem. 264 (3): 1702–9. PMID 2912980.
- Drew PD, Nagle JW, Canning RD, et al. (1995). "Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA". Gene 159 (2): 215–8. doi:10.1016/0378-1119(95)00145-V. PMID 7622052.
- Moorefield B, Roeder RG (1994). "Purification and characterization of human transcription factor IIIA". J. Biol. Chem. 269 (33): 20857–65. PMID 8063702.
- Fridell RA, Fischer U, Lührmann R, et al. (1996). "Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev". Proc. Natl. Acad. Sci. U.S.A. 93 (7): 2936–40. doi:10.1073/pnas.93.7.2936. PMC 39738. PMID 8610146.
- Oettel S, Härtel F, Kober I, et al. (1997). "Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes". Nucleic Acids Res. 25 (12): 2440–7. doi:10.1093/nar/25.12.2440. PMC 146769. PMID 9171097.
- Moreland RJ, Dresser ME, Rodgers JS, et al. (2000). "Identification of a transcription factor IIIA-interacting protein". Nucleic Acids Res. 28 (9): 1986–93. doi:10.1093/nar/28.9.1986. PMC 103300. PMID 10756201.
- Rao DS, Chang JC, Kumar PD, et al. (2001). "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors". Mol. Cell. Biol. 21 (22): 7796–806. doi:10.1128/MCB.21.22.7796-7806.2001. PMC 99949. PMID 11604514.
- Hanas JS, Hocker JR, Cheng YG, et al. (2002). "cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA". Gene 282 (1–2): 43–52. doi:10.1016/S0378-1119(01)00796-X. PMID 11814676.
- Weser S, Riemann J, Seifart KH, Meissner W (2003). "Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene". Nucleic Acids Res. 31 (9): 2408–16. doi:10.1093/nar/gkg345. PMC 154231. PMID 12711686.
- Pellikainen JM, Ropponen KM, Kataja VV, et al. (2005). "Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis". Clin. Cancer Res. 10 (22): 7621–8. doi:10.1158/1078-0432.CCR-04-1061. PMID 15569994.
- Paing MM, Johnston CA, Siderovski DP, Trejo J (2006). "Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization". Mol. Cell. Biol. 26 (8): 3231–42. doi:10.1128/MCB.26.8.3231-3242.2006. PMC 1446942. PMID 16581796.
- Yamashita A, Takada T, Nemoto K, et al. (2006). "Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage". FEBS Lett. 580 (17): 4121–5. doi:10.1016/j.febslet.2006.06.057. PMID 16828750.
- Schwartz B, Melnikova VO, Tellez C, et al. (2007). "Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo". Oncogene 26 (28): 4049–58. doi:10.1038/sj.onc.1210193. PMID 17224907.
- Hannay JA, Liu J, Zhu QS, et al. (2007). "Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation". Mol. Cancer Ther. 6 (5): 1650–60. doi:10.1158/1535-7163.MCT-06-0636. PMID 17513613.
[edit] External links
- GTF3A protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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