MTA3

This article is about proteins. For the Islamic TV channel, see MTA 3.

Metastasis associated 1 family, member 3
PDB rendering based on 2crg.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2crg
Identifiers
Symbols	MTA3; KIAA1266
External IDs	OMIM: 609050 MGI: 2151172 HomoloGene: 14282 GeneCards: MTA3 Gene
Gene Ontology Molecular function • chromatin binding • sequence-specific DNA binding transcription factor activity • zinc ion binding • sequence-specific DNA binding • metal ion binding Cellular component • nucleus • nucleolus • cytoplasm • intracellular membrane-bounded organelle Biological process • regulation of transcription, DNA-dependent Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57504	116871
Ensembl	ENSG00000057935	ENSMUSG00000055817
UniProt	Q9BTC8	Q924K8
RefSeq (mRNA)	NM_020744	NM_001171052
RefSeq (protein)	NP_065795	NP_001164523
Location (UCSC)	Chr 2: 42.72 – 42.98 Mb	Chr 17: 83.71 – 83.82 Mb
PubMed search	[1]	[2]

Metastasis-associated protein MTA3 is a protein that in humans is encoded by the MTA3 gene.

Further reading

• Wade PA, Gegonne A, Jones PL et al. (1999). "Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation". Nat. Genet. 23 (1): 62–6. doi:10.1038/12664. PMID 10471500. 
• Nagase T, Ishikawa K, Kikuno R et al. (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462. 
• Venter JC, Adams MD, Myers EW et al. (2001). "The sequence of the human genome". Science 291 (5507): 1304–51. doi:10.1126/science.1058040. PMID 11181995. 
• Simpson A, Uitto J, Rodeck U, Mahoney MG (2001). "Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3". Gene 273 (1): 29–39. doi:10.1016/S0378-1119(01)00563-7. PMID 11483358. 
• Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. 
• Yao YL, Yang WM (2004). "The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity". J. Biol. Chem. 278 (43): 42560–8. doi:10.1074/jbc.M302955200. PMID 12920132. 
• Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Mishra SK, Talukder AH, Gururaj AE et al. (2004). "Upstream Determinants of Estrogen Receptor-α Regulation of Metastatic Tumor Antigen 3 Pathway". J. Biol. Chem. 279 (31): 32709–15. doi:10.1074/jbc.M402942200. PMC 1262658. PMID 15169784. 
• Fujita N, Kajita M, Taysavang P, Wade PA (2005). "Hormonal regulation of metastasis-associated protein 3 transcription in breast cancer cells". Mol. Endocrinol. 18 (12): 2937–49. doi:10.1210/me.2004-0258. PMID 15358836. 
• Fujita N, Jaye DL, Geigerman C et al. (2004). "MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation". Cell 119 (1): 75–86. doi:10.1016/j.cell.2004.09.014. PMID 15454082. 
• Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. 
• Zhang H, Singh RR, Talukder AH, Kumar R (2006). "Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway". Genes Dev. 20 (21): 2943–8. doi:10.1101/gad.1461706. PMC 1620027. PMID 17050676. 

External links

• MTA3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)