GPR78
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| G protein-coupled receptor 78 | ||||||||
|---|---|---|---|---|---|---|---|---|
| Identifiers | ||||||||
| Symbol | GPR78 | |||||||
| External IDs | OMIM: 606921 HomoloGene: 50960 IUPHAR: GPR78 GeneCards: GPR78 Gene | |||||||
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| Orthologs | ||||||||
| Species | Human | Mouse | ||||||
| Entrez | 27201 | n/a | ||||||
| Ensembl | ENSG00000155269 | n/a | ||||||
| UniProt | Q96P69 | n/a | ||||||
| RefSeq (mRNA) | NM_080819.4 | n/a | ||||||
| RefSeq (protein) | NP_543009.2 | n/a | ||||||
| Location (UCSC) | Chr 4: 8.56 – 8.62 Mb |
n/a | ||||||
| PubMed search | [1] | n/a | ||||||
Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.[1][2]
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][2]
[edit] References
- ^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
- ^ a b "Entrez Gene: GPR78 G protein-coupled receptor 78". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27201.
[edit] Further reading
- van Laar T, Schouten T, Hoogervorst E et al. (2000). "The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway". FEBS Lett. 469 (1): 123–31. doi:10.1016/S0014-5793(00)01253-9. PMID 10708769.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. //www.ncbi.nlm.nih.gov/pmc/articles/PMC139241/.
- Clark HF, Gurney AL, Abaya E et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309. //www.ncbi.nlm.nih.gov/pmc/articles/PMC403697/.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. //www.ncbi.nlm.nih.gov/pmc/articles/PMC528928/.
- Underwood SL, Christoforou A, Thomson PA et al. (2006). "Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia". Mol. Psychiatry 11 (4): 384–94. doi:10.1038/sj.mp.4001786. PMID 16389273.
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