TAS2R46
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| Taste receptor, type 2, member 46 | ||||||||
|---|---|---|---|---|---|---|---|---|
| Identifiers | ||||||||
| Symbols | TAS2R46; T2R46; T2R54 | |||||||
| External IDs | OMIM: 612774 MGI: 2681256 HomoloGene: 131216 IUPHAR: TAS2R46 GeneCards: TAS2R46 Gene | |||||||
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| Orthologs | ||||||||
| Species | Human | Mouse | ||||||
| Entrez | 259292 | 387348 | ||||||
| Ensembl | ENSG00000226761 | ENSMUSG00000059382 | ||||||
| UniProt | P59540 | Q7M721 | ||||||
| RefSeq (mRNA) | NM_176887.2 | NM_207023 | ||||||
| RefSeq (protein) | NP_795368.2 | NP_996906 | ||||||
| Location (UCSC) | Chr 12: 11.21 – 11.21 Mb |
Chr 6: 132.62 – 132.62 Mb |
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| PubMed search | [1] | [2] | ||||||
Taste receptor type 2 member 46 is a protein that in humans is encoded by the TAS2R46 gene.[1][2]
[edit] References
- ^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855.
- ^ "Entrez Gene: TAS2R46 taste receptor, type 2, member 46". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=259292.
[edit] Further reading
- Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction.". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
- Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste.". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. //www.ncbi.nlm.nih.gov/pmc/articles/PMC139241/.
- Zhang Y, Hoon MA, Chandrashekar J, et al. (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.". Cell 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520.
- Conte C, Ebeling M, Marcuz A, et al. (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family.". Cytogenet. Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440.
- Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes.". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
- Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.". Genetics 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1449719/.
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