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2CBCB-NBOMe

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2CBCB-NBOMe
Systematic (IUPAC) name
N-(2-methoxybenzyl)-1-[(7R)-3-bromo-2,5-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methanamine
Clinical data
Pregnancy cat.  ?
Legal status legal
Identifiers
CAS number 1354634-09-5
ATC code  ?
ChemSpider 26234935 YesY
Chemical data
Formula C19H22BrNO3 
Mol. mass 392.286 g/mol
SMILES eMolecules & PubChem
 YesY (what is this?)  (verify)

2CBCB-NBOMe (NBOMe-TCB-2) is a compound indirectly derived from the phenethylamine series of hallucinogens, which was discovered in 2007 at Purdue University as part of the ongoing research program of the team led by David Nichols focusing on the mapping of the specific amino acid residues responsible for ligand binding to the 5HT2A receptor. 2CBCB-NBOMe acts as a potent and selective agonist for the 5-HT2A and 5-HT2C receptors, with a Ki of 0.27nM at the human 5-HT2A receptor, a similar potency to other agonists such as TCB-2, NBOMe-2C-I and bromodragonfly[1]


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