Acotiamide

Acotiamide
Systematic (IUPAC) name
	N-{2-[bis(1-methylethyl)amino]ethyl}-2-{[(2-hydroxy-4,5-dimethoxyphenyl)carbonyl]amino}-1,3-thiazole-4-carboxamide
Clinical data
Pregnancy cat.	?
Legal status	Uncontrolled
Routes	Oral
Identifiers
CAS number	185106-16-5
ATC code	None
PubChem	CID 5282338
ChemSpider	4445505
UNII	D42OWK5383
Chemical data
Formula	C21H30N4O5S
Mol. mass	450.55 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C21H30N4O5S/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26/h9-13,26H,7-8H2,1-6H3,(H,22,28)(H,23,24,27) ; Key:TWHZNAUBXFZMCA-UHFFFAOYSA-N ;
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Acotiamide (YM-443, Z-338) is an experimental acetylcholinesterase inhibitor currently undergoing clinical trials for the treatment of functional dyspepsia.^[1]

[edit] See also

^ Matsueda K, Hongo M, Tack J, Aoki H, Saito Y, Kato H (January 2010). "Clinical trial: dose-dependent therapeutic efficacy of acotiamide hydrochloride (Z-338) in patients with functional dyspepsia - 100 mg t.i.d. is an optimal dosage". Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society 22 (6): 618–e173. DOI:10.1111/j.1365-2982.2009.01449.x. PMID 20059698.

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