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Levomethorphan

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Levomethorphan
Systematic (IUPAC) name
3-methoxy-17-methylmorphinan
Clinical data
MedlinePlus a682492
Pregnancy cat.  ?
Legal status Schedule II
Pharmacokinetic data
Half-life 3-6 hours
Identifiers
CAS number 125-68-8 N
ATC code R05DA09
PubChem CID 5702040
DrugBank DB00514
ChemSpider 4642423 YesY
UNII 7ZZ22K9QE6 YesY
ChEBI CHEBI:4470 YesY
ChEMBL CHEMBL282713 N
Chemical data
Formula C18H25NO 
Mol. mass 271.397 g/mol
SMILES eMolecules & PubChem
 N (what is this?)  (verify)

Levomethorphan is the l-stereoisomer of methorphan. The effects of the two isomers are quite different. Dextromethorphan is an antitussive at low doses and a dissociative at much higher doses, whereas levomethorphan is an opioid analgesic. Levomethorphan has effects similar to levorphanol but is less potent as it must be demethylated to the active form by liver enzymes before becoming active.

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