Nalorphine

Nalorphine

Systematic (IUPAC) name
(5α,6α)-17-allyl- 7,8-didehydro- 4,5-epoxymorphinan- 3,6-diol
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	62-67-9 Y
ATC code	V03AB02
PubChem	CID 5284595
IUPHAR ligand	1629
ChemSpider	4447643 Y
UNII	U59WB2WRY2 N
ChEMBL	CHEMBL415284 N
Synonyms	(−)−(5R,6S)-9α-allyl- 4,5-epoxymorphin- 7-en- 3,6-diol
Chemical data
Formula	C19H21NO3
Mol. mass	311.375 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C19H21NO3/c1-2-8-20-9-7-19-12-4-6-15(22)18(19)23-17-14(21)5-3-11(16(17)19)10-13(12)20/h2-6,12-13,15,18,21-22H,1,7-10H2/t12-,13+,15-,18-,19-/m0/s1 Y Key:UIQMVEYFGZJHCZ-SSTWWWIQSA-N Y
N (what is this?)  (verify)

Nalorphine (INN, also known as N-allyl-normorphine) trade names Lethidrone and Nalline. Nalorphine acts at two opioid receptors, at the mu receptor it has antagonistic effects and at the kappa receptors it exerts agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.