HTR3E

5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
Identifiers
Symbols	HTR3E; 5-HT3-E; 5-HT3E; 5-HT3c1
External IDs	OMIM: 610123 HomoloGene: 50735 IUPHAR: 5-HT3E ChEMBL: 3812 GeneCards: HTR3E Gene
Gene Ontology Molecular function • extracellular ligand-gated ion channel activity Cellular component • plasma membrane • integral to membrane • postsynaptic membrane Biological process • ion transmembrane transport • transmembrane transport Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	285242	n/a
Ensembl	ENSG00000186038	n/a
UniProt	A5X5Y0	n/a
RefSeq (mRNA)	NM_001256613.1	n/a
RefSeq (protein)	NP_001243542.1	n/a
Location (UCSC)	Chr 3: 183.81 – 183.82 Mb	n/a
PubMed search	[1]	n/a

5-hydroxytryptamine receptor 3E is a protein that in humans is encoded by the HTR3E gene. The protein encoded by this gene is a subunit of the 5-HT3 receptor.

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. //www.ncbi.nlm.nih.gov/pmc/articles/PMC139241/.
• Karnovsky AM, Gotow LF, McKinley DD, et al. (2003). "A cluster of novel serotonin receptor 3-like genes on human chromosome 3". Gene 319: 137–48. doi:10.1016/S0378-1119(03)00803-5. PMID 14597179.
• Nalivaiko E, Sgoifo A (2009). "Central 5-HT receptors in cardiovascular control during stress". Neuroscience and biobehavioral reviews 33 (2): 95–106. doi:10.1016/j.neubiorev.2008.05.026. PMID 18573276.
• Kapeller J, Houghton LA, Mönnikes H, et al. (2008). "First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome". Hum. Mol. Genet. 17 (19): 2967–77. doi:10.1093/hmg/ddn195. PMID 18614545.

External links

• HTR3E+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)