Phosmet
From Wikipedia, the free encyclopedia
| Phosmet[1] | |
|---|---|
 |
|
|
2-(Dimethoxyphosphinothioylthiomethyl)isoindoline-1,3-dione |
|
|
Other names
Fosmet |
|
| Identifiers | |
| CAS number | 732-11-6  |
| PubChem | 12901 |
| ChemSpider | 12367 |
| UNII | VN04LI540Y |
| KEGG | C18756 |
| ChEBI | CHEBI:38786 |
| ATCvet code | QP53,QP53BB03 |
| Jmol-3D images | Image 1 |
|
|
|
|
| Properties | |
| Molecular formula | C11H12NO4PS2 |
| Molar mass | 317.32 g mol−1 |
| Appearance | White to off-white crystals |
| Density | 1.03 g/cm3 |
| Melting point |
72 °C, 345 K, 162 °F |
| Boiling point |
Decomposes at >100 °C |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
|
| Infobox references |
Phosmet is a phthalimide-derived, non-systemic, organophosphate insecticide used on plants and animals. It is mainly used on apple trees for control of coddling moth, though it is also used on a wide range of fruit crops, ornamentals, and vines for the control of aphids, suckers, mites, and fruit flies.[2]
[edit] Safety
Phosmet is on the US Emergency Planning List of Extremely Hazardous Substances. It is highly toxic to bees.[2]
Mark Purdey has made the controversial suggestion that phosmet may have played a key role in the epidemic of bovine spongiform encephalopathy (BSE).[3]
A 2010 study found that each 10-fold increase in urinary concentration of organophosphate metabolites was associated with a 55% to 72% increase in the odds of ADHD in children.[4]
[edit] References
- ^ "Phosmet Safety Card". http://www.itcilo.it/english/actrav/telearn/osh/ic/732116.htm. Retrieved 2006-08-06.
- ^ a b "Toxicology of Phosmet" (Webpage). http://extoxnet.orst.edu/pips/phosmet.htm. Retrieved 2006-08-06.
- ^ Purdey M (1998). "High-dose exposure to systemic phosmet insecticide modifies the phosphatidylinositol anchor on the prion protein: the origins of new variant transmissible spongiform encephalopathies?". Med. Hypotheses 50 (2): 91–111. doi:10.1016/S0306-9877(98)90194-3. PMID 9572563.
- ^ http://www.medscape.com/viewarticle/721892
|
