Spiroxatrine

Spiroxatrine
IUPAC name 8-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Identifiers
CAS number	1054-88-2 N
PubChem	5268
ChemSpider	5078 Y
MeSH	Spiroxatrine
ChEMBL	CHEMBL300555 Y
IUPHAR ligand	53
Jmol-3D images	Image 1
SMILES O=C2NCN(c1ccccc1)C23CCN(CC3)CC4Oc5ccccc5OC4
InChI InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26) Y Key: JVGBTTIJPBFLTE-UHFFFAOYSA-N Y InChI=1/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26) Key: JVGBTTIJPBFLTE-UHFFFAOYAW
Properties
Molecular formula	C22H25N3O3
Molar mass	379.45 g mol−1
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Spiroxatrine is drug which acts as a selective antagonist at both the 5-HT_1A receptor and the α_2C adrenergic receptor. It is an analogue of spiperone, and also has some dopamine antagonist effects.