Indoramin
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| Systematic (IUPAC) name | |
| N-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}benzamide | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 26844-12-2  |
| ATC code | C02CA02 |
| PubChem | CID 33625 |
| IUPHAR ligand | 501 |
| ChemSpider | 31014  |
| UNII | 0Z802HMY7H |
| KEGG | D04531 |
| ChEMBL | CHEMBL279516 |
| Chemical data | |
| Formula | C22H25N3O |
| Mol. mass | 347.454 g/mol |
| SMILES | eMolecules & PubChem |
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Indoramin (trade name Baratol) is a piperidine antiadrenergic agent.
It is an alpha-1 selective adrenoceptor antagonist[1] with direct myocardial depression action; therefore, it results in no reflex tachycardia.
It is commonly synthesized from tryptophol.[2]
[edit] References
- ^ Pierce V, Shepperson NB, Todd MH, Waterfall JF (February 1986). "Investigation into the cardioregulatory properties of the alpha 1-adrenoceptor blocker indoramin". Br. J. Pharmacol. 87 (2): 433–441. PMC 1916533. PMID 3955309. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1916533.
- ^ Ullman's encyclopedia of Industrial Chemistry, Sixth Edition, 2002.
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