Alizapride

Alizapride
Systematic (IUPAC) name
	N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral, IM, IV
Pharmacokinetic data
Half-life	3 hours
Excretion	Renal
Identifiers
CAS number	59338-93-1
ATC code	A03FA05
PubChem	CID 43008
DrugBank	DB01425
ChemSpider	39202
UNII	P55703ZRZY
KEGG	D07102
ChEMBL	CHEMBL290194
Chemical data
Formula	C16H21N5O2
Mol. mass	315.37 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C16H21N5O2/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20) ; Key:KSEYRUGYKHXGFW-UHFFFAOYSA-N ;
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Alizapride (Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide and other benzamides.^[1]

[edit] See also

Anon., Drugs Future 1981, 6, 11.

^ Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M (1988). "Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial". Cancer Chemother Pharmacol 22 (4): 316–20. PMID 3048762.

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