Clebopride

Clebopride
Systematic (IUPAC) name
	4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-; 2-methoxybenzamide
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	55905-53-8
ATC code	A03FA06
PubChem	CID 2780
ChemSpider	2678
UNII	I0A84520Y9
KEGG	D03534
ChEMBL	CHEMBL325109
Chemical data
Formula	C20H24ClN3O2
Mol. mass	373.876 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) ; Key:BVPWJMCABCPUQY-UHFFFAOYSA-N ;
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Clebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it is a substituted benzamide, closely related to metoclopramide.

A small Spanish study found that more adverse reactions are reported with clebopride than with metoclopramide, particularly extrapyramidal symptoms.^[1]

[edit] References

^ Cuena Boy R, Maciá Martínez MA (1998). "[Extrapyramidal toxicity caused by metoclopramide and clebopride: study of voluntary notifications of adverse effects to the Spanish Drug Surveillance System]" (in Spanish). Atencion Primaria 21 (5): 289–95. PMID 9608114. Free full text

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