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Tritoqualine

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Tritoqualine
Systematic (IUPAC) name
7-amino-4,5,6-triethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 14504-73-5
ATC code  ?
PubChem CID 72145
ChemSpider 65119
UNII F4MW5166YH YesY
Chemical data
Formula C26H32N2O8
Mol. mass 500.54 g/mol
SMILES eMolecules & PubChem

Tritoqualine, also known as hypostamine, is an inhibitor of the enzyme histidine decarboxylase and therefore an atypical antihistamine, used for the treatment of urticaria and allergic rhinitis[1] with no known adverse effects.

[edit] References

  1. ^ Randomized, placebo controlled study of tritoqualine (hypostamine*) in the treatment of perennial allergic rhinitis. A. Pradalier, V. Hentschel, S. Prouzeau, D. Legallais, G. Lefrançois. Revue Française d’Allergologie et d’Immunologie Clinique 43:175-179 (2003)



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