Tertatolol
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| Systematic (IUPAC) name | |
| (±)-1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ℞ Prescription only |
| Routes | Oral |
| Identifiers | |
| CAS number | 34784-64-0  |
| ATC code | C07AA16 |
| PubChem | CID 36920 |
| IUPHAR ligand | 571 |
| UNII | 9ZO341YQXP  |
| KEGG | D07182 |
| ChEMBL | CHEMBL434200 |
| Chemical data | |
| Formula | C16H25NO2S |
| Mol. mass | 295.44 g/mol |
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Tertatolol (Artex, Artexal, Prenalex) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It was discovered by the French pharmaceutical company Servier and is marketed in Europe.[1]
Tertatolol has also been shown to act as a 5-HT1A receptor antagonist, similarly to pindolol.[2][3]
[edit] See also
[edit] References
- ^ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0. http://books.google.com/books?id=5GpcTQD_L2oC&lpg=PA1002&pg=PA1002#v=onepage&q=&f=false.
- ^ Jolas T, Haj-Dahmane S, Lanfumey L, et al. (May 1993). "(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain". Naunyn-Schmiedeberg's Archives of Pharmacology 347 (5): 453–63. PMID 7686633.
- ^ Soudijn, W.; Olivier, Berend; Wijngaarden, I. van (1997). Serotonin receptors and their ligands. Amsterdam: Elsevier. ISBN 0-444-82041-8. http://books.google.com/books?id=lfo0hGqIex0C&lpg=PA37&pg=PA37#v=onepage&q=&f=false.
[edit] External links
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