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UH-301

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UH-301
Systematic (IUPAC) name
(S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 127126-22-1
ATC code  ?
IUPHAR ligand 61
Chemical data
Formula C16H24FNO 
Mol. mass 265.365 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

UH-301 is a drug and research chemical widely used in scientific studies. It acts as a selective 5-HT1A receptor silent antagonist.[1] It is structurally related to 8-OH-DPAT.[1]

[edit] References

  1. ^ a b Björk L, Cornfield LJ, Nelson DL, Hillver SE, Andén NE, Lewander T, Hacksell U. (1991). "Pharmacology of the novel 5-hydroxytryptamine1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects.". J Pharmacol Exp Ther. 258 (1): 58–65. PMID 1830099. 



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