Aquayamycin

Aquayamycin
	IUPAC name (3R,4aR,12bS)-9-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]-3,4a,8,12b-tetrahydroxy-3-methyl-2,4-dihydrobenzo[a]anthracene-1,7,12-trione
Identifiers
CAS number	26055-63-0
PubChem	73441
ChemSpider	66147
MeSH	aquayamycin
Jmol-3D images	Image 1
	SMILES C[C@@H]1[C@H]([C@@H](C[C@@H](O1)C2=C(C3=C(C=C2)C(=O)C4=C(C3=O)C=C[C@]5([C@@]4(C(=O)C[C@](C5)(C)O)O)O)O)O)O ;
	InChI InChI=1S/C25H26O10/c1-10-19(28)14(26)7-15(35-10)11-3-4-12-17(20(11)29)21(30)13-5-6-24(33)9-23(2,32)8-16(27)25(24,34)18(13)22(12)31/h3-6,10,14-15,19,26,28-29,32-34H,7-9H2,1-2H3/t10-,14-,15-,19-,23+,24+,25+/m1/s1 ; Key: KCOULPRVOZDQEL-IFNZWHIZSA-N InChI=1/C25H26O10/c1-10-19(28)14(26)7-15(35-10)11-3-4-12-17(20(11)29)21(30)13-5-6-24(33)9-23(2,32)8-16(27)25(24,34)18(13)22(12)31/h3-6,10,14-15,19,26,28-29,32-34H,7-9H2,1-2H3/t10-,14-,15-,19-,23+,24+,25+/m1/s1; Key: KCOULPRVOZDQEL-IFNZWHIZBY ;
Properties
Molecular formula	C25H26O10
Molar mass	486.47 g/mol
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references

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Aquayamycin is an anthraquinones derivative.^[2] It is an inhibitor of the enzyme tyrosine hydroxylase.

Saquayamycins (saquayamycins A, B, C and D) are antibiotics of the aquayamycin group found in Streptomyces nodosus cultures broth.^[3]

[edit] References

^ Aquayamycin - Compound Summary, PubChem.
^ The structure of aquayamycin. M. Sezaki, S. Kondo, K. Maeda, H. Umezawa and M. Ohno, Tetrahedron, Volume 26, Issue 22, 1970, pages 5171-5190, doi:10.1016/S0040-4020(01)98726-5
^ Saquayamycins, new aquayamycin-group antibiotics. Uchida T, Imoto M, Watanabe Y, Miura K, Dobashi T, Matsuda N, Sawa T, Naganawa H, Hamada M, Takeuchi T. J Antibiot (Tokyo). 1985 Sep;38(9), pages 1171-1181, PubMed

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