Amitraz
| Amitraz | |
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N,N'-[(methylimino)dimethylidyne]di-2,4-xylidine |
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| Identifiers | |
| CAS number | 33089-61-1  |
| PubChem | 36324 |
| ChemSpider | 33405 |
| UNII | 33IAH5017S |
| KEGG | D02380 |
| ChEMBL | CHEMBL1365675  |
| ATCvet code | QP53 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C19H23N3 |
| Molar mass | 293.41 g/mol |
| Melting point |
86–87°C |
| Solubility in water | Insoluble |
| Vapor pressure | 2.6 x 10-6 mm Hg. |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references |
Amitraz is an antiparasitic drug. Product names include Ridd, Aazdieno, Acarac, Aludex, Amitraze, Avartin, Baam, Edrizan, Maitac, Mitac, Mitaban, Triatox, Triatix, Vapcozin Taktic, Triazid, Topline, Tudy, Ectodex, Garial, Danicut, Ovidrex, Acadrex, Bumetran, and Ovasyn.
It is an alpha-adrenergic agonist.[1]
[edit] Uses
Amitraz is a triazapentadiene compound, a member of the amidine class. It is an insecticide and acaricide used to control red spider mites, leaf miners, scale insects, and aphids in which the mechanism of action is similar to other α2-adrenoreceptors agonists as well as by the inhibition of the enzyme monoamine oxidase. Sedation, analgesic effects and cardiovascular depression similar to the α2-adrenoreceptors agonists have been described in several species after amitraz injection. On cotton it is used to control bollworms, white fly, and leaf worms. On animals it is used to control ticks, mites, lice and other animal pests. The United States Environmental Protection Agency classifies amitraz as Class III - slightly toxic.
It cannot be used on horses, because it can cause irreversible gut stasis.
[edit] References
- ^ Young FM, Menadue MF, Lavranos TC (November 2005). "Effects of the insecticide amitraz, an alpha2-adrenergic receptor agonist, on human luteinized granulosa cells". Hum. Reprod. 20 (11): 3018–25. doi:10.1093/humrep/dei194. PMID 16085667. http://humrep.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=16085667.
[edit] External links
- Amitraz profile from EXTOXNET, maintained by Cornell University
- Amitraz profile from catalogue of Sigma-Aldrich
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