Noribogaine
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| Systematic (IUPAC) name | |
| 12-Hydroxyibogamine | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? (US) C-I Analogue |
| Routes | Metabolite of Iboga-alkaloid(s?) Ibogaine. |
| Identifiers | |
| CAS number | 481-88-9 |
| ATC code | ? |
| PubChem | CID 3083548 |
| ChemSpider | 2340735  |
| Chemical data | |
| Formula | C19H24N2O |
| Mol. mass | 296.407 g/mol |
| SMILES | eMolecules & PubChem |
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Noribogaine, or 12-hydroxyibogamine, is a major active metabolite of ibogaine, and is thought to be involved in the anti-addictive effects of ibogaine-containing plant extracts.[1][2][3]
[edit] See also
- Dissociative
- Ibogaine
- 18-Methoxycoronaridine
- Voacangine
- Memantine
- Opioids ie:
- Dextropropoxyphene
- Methadone
- Dextromethorphan
- Mitragynine, 7-hydroxymitragynine(Kratom)
- Salvinorin A(Salvia Divinorum)
[edit] References
- ^ Glick SD, Maisonneuve IS (May 1998). "Mechanisms of antiaddictive actions of ibogaine". Annals of the New York Academy of Sciences 844: 214–26. doi:10.1111/j.1749-6632.1998.tb08237.x. PMID 9668680.
- ^ Baumann MH, Pablo J, Ali SF, Rothman RB, Mash DC (2001). "Comparative neuropharmacology of ibogaine and its O-desmethyl metabolite, noribogaine". The Alkaloids. Chemistry and Biology 56: 79–113. doi:10.1016/S0099-9598(01)56009-5. PMID 11705118.
- ^ Kubiliene A, Marksiene R, Kazlauskas S, Sadauskiene I, Razukas A, Ivanov L (2008). "Acute toxicity of ibogaine and noribogaine". Medicina (Kaunas, Lithuania) 44 (12): 984–8. PMID 19142057.
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