DCKA

DCKA
	IUPAC name 5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid
Identifiers
CAS number	131123-76-7
PubChem	1779
IUPHAR ligand	2361
Jmol-3D images	Image 1
	SMILES C1=C(C=C2C(=C1Cl)C(=O)C=C(N2)C(=O)O)Cl ;
Properties
Molecular formula	C10H5Cl2NO3
Molar mass	258.058 g/mol
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references

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DCKA (5,7-dichlorokynurenic acid) is a selective NMDA receptor (NMDAR) antagonist acting at the glycine site on the NMDAR complex.^[1]

[edit] References

^ McNamara D, Smith EC, Calligaro DO, O'Malley PJ, McQuaid LA, Dingledine R. 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neuroscience Letters. 1990 Nov 27;120(1):17-20. PMID 2149877

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