Iodophenpropit
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| Iodophenpropit | |
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3-(1H-imidazol-5-yl)propyl N'-[2-(4-iodophenyl)ethyl]imidothiocarbamate |
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Other names
1-[3-(3H-imidazol-4-yl)propylthio]-N'-[2-(4-iodophenyl)ethyl]formamidine |
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| Identifiers | |
| CAS number | 143407-29-8 |
| PubChem | 3035746 |
| MeSH | Iodophenpropit |
| ChEMBL | CHEMBL498770 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C15H19IN4S |
| Molar mass | 414.30763 |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references |
Iodophenpropit is a histamine antagonist which binds selectively to the H3 subtype. Its 125I radiolabelled form is used for mapping the distribution of H3 receptors in the body.[1][2]
[edit] References
- ^ Jansen, FP; Wu, TS; Voss, HP; Steinbusch, HW; Vollinga, RC; Rademaker, B; Bast, A; Timmerman, H (1994). "Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, 125I-iodophenpropit, to rat brain". British journal of pharmacology 113 (2): 355–62. PMC 1510107. PMID 7834183. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1510107.
- ^ Jansen, FP; Mochizuki, T; Maeyama, K; Leurs, R; Timmerman, H (2000). "Characterization of histamine H3 receptors in mouse brain using the H3 antagonist 125Iiodophenpropit". Naunyn-Schmiedeberg's archives of pharmacology 362 (1): 60–7. PMID 10935534.
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