Mesembrine

Mesembrine
	IUPAC name (3aS,7aR)-3a- (3,4-dimethoxyphenyl)- 1-methyl-2,3,4,5,7,7a- hexahydroindol-6-one
Identifiers
CAS number	468-53-1
PubChem	193296
ChemSpider	167737
Jmol-3D images	Image 1
	SMILES CN1CC[C@@]2 ([C@H]1CC(=O)CC2) C3=CC(=C(C=C3)OC)OC ;
	InChI InChI=1S/C17H23NO3/c1-18-9-8-17(7-6-13(19)11-16(17)18)12-4-5-14(20-2)15(10-12)21-3/h4-5,10,16H,6-9,11H2,1-3H3/t16-,17-/m1/s1 ; Key: DAHIQPJTGIHDGO-IAGOWNOFSA-N InChI=1/C17H23NO3/c1-18-9-8-17(7-6-13(19)11-16(17)18)12-4-5-14(20-2)15(10-12)21-3/h4-5,10,16H,6-9,11H2,1-3H3/t16-,17-/m1/s1; Key: DAHIQPJTGIHDGO-IAGOWNOFBH ;
Properties
Molecular formula	C17H23NO3
Molar mass	289.37 g mol−1
log P	1.1
Supplementary data page
Structure and; properties	n, εr, etc.
Thermodynamic; data	Phase behaviour; Solid, liquid, gas
Spectral data	UV, IR, NMR, MS
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references

From Wikipedia, the free encyclopedia

Jump to: navigation, search

Mesembrine is an alkaloid present in Sceletium tortuosum.^[1] Mesembrine acts as a serotonin reuptake inhibitor. Mesembrine may contribute to the antidepressant effects of kanna. ^[2]

[edit] References

^ Smith, M. T.; Crouch, N. R.; Gericke, N.; Hirst, M. (1996). "Psychoactive constituents of the genus Sceletium N.E.Br. And other Mesembryanthemaceae: A review". Journal of ethnopharmacology 50 (3): 119–130. doi:10.1016/0378-8741(95)01342-3. PMID 8691846. edit
^ Stafford, G. I.; Pedersen, M. E.; Van Staden, J.; Jäger, A. K. (2008). "Review on plants with CNS-effects used in traditional South African medicine against mental diseases". Journal of Ethnopharmacology 119 (3): 513–537. doi:10.1016/j.jep.2008.08.010. PMID 18775771. edit