Amezinium metilsulfate

Amezinium metilsulfate
Systematic (IUPAC) name
	6-Methoxy-1-phenylpyridazin-1-ium-4-amine; methyl sulfate
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	30578-37-1
ATC code	C01CA25
PubChem	CID 71926
ChemSpider	64937
UNII	03NR868ICX
KEGG	D01304
Chemical data
Formula	C12H15N3O5S
Mol. mass	313.32 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C11H11N3O.CH4O4S/c1-15-11-7-9(12)8-13-14(11)10-5-3-2-4-6-10;1-5-6(2,3)4/h2-8,12H,1H3;1H3,(H,2,3,4) ; Key:ZEASXVYVFFXULL-UHFFFAOYSA-N ;
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Amezinium metilsulfate (INN, trade name Regulton) is a sympathomimetic drug used for the treatment of low blood pressure. It has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.^[1]^[2]

[edit] References

^ Araújo, D; Caramona, MM; Osswald, W (1983). "On the mechanism of action of amezinium methylsulphate on the dog saphenous vein". European journal of pharmacology 90 (2-3): 203–14. doi:10.1016/0014-2999(83)90238-8. PMID 6873182. edit
^ Lenke, D.; Gries, J.; Kretzschmar, R. (1981). "Pharmacology of amezinium, a novel antihypotensive drug. III. Studies on the mechanism of action". Arzneimittel-Forschung 31 (9a): 1558–1565. PMID 7197970. edit

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