From Wikipedia, the free encyclopedia
gamma-Hydroxyvaleric acid (GHV) is a psychoactive drug and designer drug which is structurally and pharmacologically related to both gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acid (GABA). It is sometimes seen on the black market as a legal alternative to GHB, but with lower potency and higher toxicity,[1] which has tended to limit its recreational abuse.
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[edit] References
- ^ Carter LP, Chen W, Wu H, Mehta AK, Hernandez RJ, Ticku MK, Coop A, Koek W et al (April 2005). "Comparison of the behavioral effects of gamma-hydroxybutyric acid (GHB) and its 4-methyl-substituted analog, gamma-hydroxyvaleric acid (GHV)". Drug and Alcohol Dependence 78 (1): 91–9. doi:10.1016/j.drugalcdep.2004.10.002. PMID 15769562.
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| GABAA agonists/PAMs |
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| GABAB agonists |
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| H1 inverse agonists |
Antihistamines: Captodiame • Cyproheptadine • Diphenhydramine • Doxylamine • Hydroxyzine • Methapyrilene • Pheniramine • Promethazine • Propiomazine
Antidepressants: Tricyclic antidepressants ( Amitriptyline, Doxepin, Trimipramine, etc.) • Tetracyclic antidepressants ( Mianserin, Mirtazapine, etc.)
Antipsychotics: Typical antipsychotics ( Chlorpromazine, Thioridazine, etc.) • Atypical antipsychotics ( Olanzapine, Quetiapine, Risperidone, etc.)
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| α1-Adrenergic antagonists |
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| α2-Adrenergic agonists |
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| 5-HT2A antagonists |
Antidepressants: Serotonin antagonists and reuptake inhibitors ( Trazodone) • Tricyclic antidepressants ( Amitriptyline, Doxepin, Trimipramine, etc.) • Tetracyclic antidepressants ( Mianserin, Mirtazapine, etc.)
Antipsychotics: Typical antipsychotics ( Chlorpromazine, Thioridazine, etc.) • Atypical antipsychotics ( Olanzapine, Quetiapine, Risperidone, etc.)
Others: Eplivanserin • Niaprazine • Pruvanserin • Volinanserin
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| Melatonin agonists |
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| Orexin antagonists |
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| Others |
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