Surugatoxin
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| Systematic (IUPAC) name | |
|---|---|
| [(3S)-2,3,4,5,6-pentahydroxycyclohexyl] (6aS,8R,9S,11aS)-6'-bromo-6a,9-dihydroxy-9-methyl-1,2',3,10-tetraoxo-spiro[4,6,7,11a-tetrahydropyrido[1,2-f]pteridine-8,3'-indoline]-7-carboxylate | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 40957-92-4 |
| ATC code | ? |
| PubChem | CID 3034617 |
| ChemSpider | 10472966 |
| Chemical data | |
| Formula | C25H26BrN5O13 |
| Mol. mass | 684.40 g/mol |
| SMILES | eMolecules & PubChem |
Surugatoxin is a type of venom found in the Japanese ivory mollusk (Babylonia japonica). It functions as a ganglionic blocker of nicotinic acetylcholine receptors.[1][2]
[edit] References
- ^ Yamada, S.; Hayashi, E. (April 1979). "Effects of Surugatoxin on Adrenergically Innervated Tissues" (pdf). Japanese Journal of Pharmacology 29 (2): 295–302. doi:10.1254/jjp.29.295. PMID 537251. http://www.journalarchive.jst.go.jp/jnlpdf.php?cdjournal=jphs1951&cdvol=29&noissue=2&startpage=295&lang=en.
- ^ Hayashi, E.; Yamada, S. (1975). "Pharmacological Studies on Surugatoxin, the Toxic Principle from Japanese Ivory Mollusc (Babylonia japonica)" (pdf). British Journal of Pharmacology 53 (2): 207–215. PMC 1666298. PMID 238699. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666298/pdf/brjpharm00523-0054.pdf.
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