3-Fluoroamphetamine
From Wikipedia, the free encyclopedia
| Systematic (IUPAC) name | |
|---|---|
| (RS)-1-(3-fluorophenyl)propan-2-amine | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 1626-71-7 |
| ATC code | ? |
| PubChem | CID 121501 |
| ChemSpider | 108417 |
| Chemical data | |
| Formula | C9H12FN |
| Mol. mass | 153.196 |
| SMILES | eMolecules & PubChem |
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3-Fluoroamphetamine (3-FA; PAL-353) is a stimulant drug from the amphetamine family which acts as a monoamine releaser with similar potency to methamphetamine but more selectivity for dopamine and noradrenaline release over serotonin.[1] It is self-administered by mice to a similar extent to related drugs such as 4-fluoroamphetamine and 3-methylamphetamine.[2]
[edit] See also
- 2-Fluoroamphetamine (2-FA)
- 3-Fluoroethamphetamine (3-FEA)
- 3-Fluoromethamphetamine (3-FMA)
- 3-Hydroxyamphetamine (Gepefrine)
- 3-Methylamphetamine (3-MA)
- 3-Methoxyamphetamine (3-MeOA)
- 3-Trifluoromethylamphetamine (Norfenfluramine)
- 4-Fluoroamphetamine (4-FA)
[edit] References
- ^ Negus, SS; Mello, NK; Blough, BE; Baumann, MH; Rothman, RB (2007). "Monoamine releasers with varying selectivity for dopamine/norepinephrine versus serotonin release as candidate "agonist" medications for cocaine dependence: studies in assays of cocaine discrimination and cocaine self-administration in rhesus monkeys". The Journal of pharmacology and experimental therapeutics 320 (2): 627–36. doi:10.1124/jpet.106.107383. PMID 17071819.
- ^ Wee, S; Anderson, KG; Baumann, MH; Rothman, RB; Blough, BE; Woolverton, WL (2005). "Relationship between the serotonergic activity and reinforcing effects of a series of amphetamine analogs". The Journal of pharmacology and experimental therapeutics 313 (2): 848–54. doi:10.1124/jpet.104.080101. PMID 15677348.

