3,4-Dihydroxystyrene
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| Systematic (IUPAC) name | |
|---|---|
| 4-vinylbenzene-1,2-diol | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | Uncontrolled |
| Identifiers | |
| CAS number | 6053-02-7 |
| ATC code | None |
| PubChem | CID 151398 |
| ChemSpider | 133430 |
| KEGG | C06224 |
| Chemical data | |
| Formula | C8H8O2 |
| Mol. mass | 136.15 g/mol |
| SMILES | eMolecules & PubChem |
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3,4-Dihydroxystyrene (DHS) is a centrally-acting inhibitor of the enzyme phenylalanine hydroxylase (PH).[1] It is likely that DHS and other PH inhibitors will never have clinical applications on account of their capacity for inducing hyperphenylalaninemia and phenylketonuria.
[edit] See also
[edit] References
- ^ Koizumi S, Matsushima Y, Nagatsu T, Iinuma H, Takeuchi T, Umezawa H (September 1984). "3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases". Biochimica Et Biophysica Acta 789 (2): 111–8. doi:10.1016/0167-4838(84)90194-8. PMID 6148105. http://linkinghub.elsevier.com/retrieve/pii/0167-4838(84)90194-8.
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