HOT-2

HOT-2
IUPAC name N-[2-(4-Ethylsulfanyl-2,5-dimethoxy-phenyl)-ethyl]-hydroxylamine
Other names 2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanaminol
Identifiers
CAS number	207740-38-3
ChemSpider	21106320 Y
ChEMBL	CHEMBL127595 Y
Jmol-3D images	Image 1
SMILES CCSc1cc(OC)c(cc1OC)CCNO
InChI InChI=1S/C12H19NO3S/c1-4-17-12-8-10(15-2)9(5-6-13-14)7-11(12)16-3/h7-8,13-14H,4-6H2,1-3H3 Y Key: XGFJCRNRWOXGQM-UHFFFAOYSA-N Y InChI=1/C12H19NO3S/c1-4-17-12-8-10(15-2)9(5-6-13-14)7-11(12)16-3/h7-8,13-14H,4-6H2,1-3H3 Key: XGFJCRNRWOXGQM-UHFFFAOYAO
Properties
Molecular formula	C12H19NO3S
Molar mass	257.347 g/mol
Melting point	122 °C
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

HOT-2, or 2,5-dimethoxy-4-(β-ethylthio)-N-hydroxyphenethylamine is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book PiHKAL (Phenethylamines i Have Known And Loved).

Chemistry

HOT-2's full chemical name is 2-[4-(2-ethylthio)-2,5-dimethoxyphenyl–N–hydroxyethanamine. It has structural properties similar to 2C-T-2 and to other drugs in the HOT- series, with the most closely related compounds being HOT-7 and HOT-17.

General information

The dosage range of HOT-2 is typically 10-18 mg and its duration is approximately 6–10 hours according to Shulgin. HOT-2 produces visuals and moving, flowing lights. It also causes euphoria and increases blood pressure.

See also

• Phenethylamine

External links

• PiHKAL #87 HOT-2
• HOT-2 Entry in PiHKAL • info