Eticyclidine
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| Systematic (IUPAC) name | |
| N-ethyl-1-phenylcyclohexylamine | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | Schedule I / Class A |
| Identifiers | |
| CAS number | 2201-15-2 |
| ATC code | None |
| PubChem | CID 16622 |
| ChemSpider | 15759  |
| UNII | O8I1LL6A89 |
| ChEMBL | CHEMBL279924 |
| Chemical data | |
| Formula | C14H21N |
| Mol. mass | 203.323 g/mol |
| SMILES | eMolecules & PubChem |
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Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400,[1] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable properties.[2] PCE is slightly more potent than PCP and has similar effects, but its unpleasant taste and tendency to cause nausea made it less accepted by users.[3] Due to its similarity in effects to PCP, PCE was placed into the Schedule 1 list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known.
[edit] See also
[edit] References
- ^ LEVY L, CAMERON DE, AITKEN RC (March 1960). "Observation on two psychotomimetic drugs of piperidine derivation--CI 395 (sernyl) and CI 400". The American Journal of Psychiatry 116: 843–4. PMID 14416411.
- ^ Kalir A, Edery H, Pelah Z, Balderman D, Porath G. 1-Phenylcycloalkylamine derivatives. II. Synthesis and pharmacological activity. Journal of Medicinal Chemistry. 1969. 12(3):473-477
- ^ Structure Activity of PCP analogs
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