BRL-44408
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| Systematic (IUPAC) name | |
| 2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 118343-19-4  |
| ATC code | ? |
| PubChem | CID 121850 |
| IUPHAR ligand | 525 |
| ChEMBL | CHEMBL216097  |
| Chemical data | |
| Formula | C13H17N3 |
| Mol. mass | 215.293 g/mol |
| SMILES | eMolecules & PubChem |
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BRL-44408 is a drug used in scientific research which acts as a selective antagonist for the α2A adrenoreceptor.[1] It has been suggested as having potential therapeutic application in the treatment of extrapyramidal side effects produced by some antipsychotic medications.[2]
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[edit] References
- ^ Alberts P (January 1993). "Subtype classification of presynaptic alpha 2-adrenoceptors". General Pharmacology 24 (1): 1–8. PMID 8387042.
- ^ Imaki J, Mae Y, Shimizu S, Ohno Y (April 2009). "Therapeutic potential of alpha2 adrenoceptor antagonism for antipsychotic-induced extrapyramidal motor disorders". Neuroscience Letters 454 (2): 143–7. doi:10.1016/j.neulet.2009.03.001. PMID 19429072.
