alpha-Methylhistamine
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| α-Methylhistamine | |
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1-(3H-Imidazol-4-yl)propan-2-amine |
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1-(1H-Imidazol-4-yl)propan-2-amine[1] |
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| Identifiers | |
| CAS number | 6986-90-9 |
| PubChem | 3615, 156615 (R), 6603865 (S) |
| ChemSpider | 3489 |
| MeSH | Alpha-methylhistamine |
| ChEBI | CHEBI:295965 |
| ChEMBL | CHEMBL116655 |
| IUPHAR ligand | 1239 |
| Jmol-3D images | Image 1 Image 2 Image 3 |
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| Properties | |
| Molecular formula | C6H11N3 |
| Molar mass | 125.17 g mol−1 |
| Exact mass | 125.095297367 g mol-1 |
| log P | -0.346 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references |
α-Methylhistamine is a histamine agonist selective for the receptor subtype H3. It causes lowering of blood pressure and a decrease of heart rate in animal models.[2]
[edit] References
- ^ https://www.ebi.ac.uk/chebi/searchId.do?chebiId=295965
- ^ McLeod, RL; Gertner, SB; Hey, JA (1993). "Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs". Br J Pharmacol 110 (2): 553–558. PMC 2175947. PMID 7902173. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2175947.
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