Rescinnamine
From Wikipedia, the free encyclopedia
| Systematic (IUPAC) name | |
|---|---|
| methyl (3β,16β,17α,18β,20α)-11,17-dimethoxy-18-{[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}yohimban-16-carboxylate | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ℞ Prescription only |
| Routes | oral |
| Identifiers | |
| CAS number | 24815-24-5 |
| ATC code | C02AA01 |
| PubChem | CID 5280954 |
| DrugBank | APRD00112 |
| ChemSpider | 4444446 |
| UNII | Q6W1F7DJ2D |
| KEGG | D00198 |
| ChEBI | CHEBI:28572 |
| ChEMBL | CHEMBL1668 |
| Synonyms | methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-{[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate |
| Chemical data | |
| Formula | C35H42N2O9 |
| Mol. mass | 634.716 g/mol |
| SMILES | eMolecules & PubChem |
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Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug.
It is an alkaloid obtained from Rauwolfia serpentina[1] and other species of Rauwolfia.
[edit] Brand names
Moderil, Cinnasil, Anaprel
[edit] References
- ^ FIFE R, MACLAURIN JC, WRIGHT JH (December 1960). "Rescinnamine in treatment of hypertension in hospital clinic and in general practice". British medical journal 2 (5216): 1848–50. doi:10.1136/bmj.2.5216.1848. PMC 2098607. PMID 13699407. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2098607.
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