SIB-1553A
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| SIB-1553A | |
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(R/S)-4-{[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio}phenol hydrochloride |
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| Identifiers | |
| CAS number | 191611-76-4  |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C13H19NOS |
| Molar mass | 237.36 g mol−1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references |
SIB-1553A is a nicotinic acetylcholine receptor agonist that is selective for receptors with a β4 subunit. Administration of SIB-1553A improved memory and attention in a Parkinson's disease model.[1]
[edit] References
- ^ Schneider, JS (July 2003). "The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys". Journal of Pharmacology and Experimental Therapeutics 306 (1): 401–6. doi:10.1124/jpet.103.051912. PMID 12721323.
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