Chlorisondamine
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| Systematic (IUPAC) name | |
| trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-isoindolin-2-ium-2-yl)ethyl]ammonium dichloride | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 7701-62-4 |
| ATC code | None |
| PubChem | CID 6244 |
| ChemSpider | 6008  |
| UNII | JD3M24F66I |
| Chemical data | |
| Formula | C14H20Cl6N2 |
| Mol. mass | 429.04 g/mol |
| SMILES | eMolecules & PubChem |
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Chlorisondamine is a nicotinic acetylcholine receptor antagonist that produces both neuronal and ganglionic blockade.
Chlorisondamine has been shown to form noncovalent complexes with various biomolecules including sphingomyelin and other associated glycolipids.[1][2][3]
[edit] References
- ^ Woods, A. S.; Moyer, S. C.; Wang, H. Y. J.; Wise, R. A., Interaction of chlorisondamine with the neuronal nicotinic acetylcholine receptor. Journal of Proteome Research 2003, 2 (2), 207-212.
- ^ Jackson, S. N.; Wang, H. Y. J.; Woods, A. S., Direct tissue analysis of phospholipids in rat brain using MALDI-TOFMS and MALDI-ion mobility-TOFMS. Journal of the American Society for Mass Spectrometry 2005, 16 (2), 133-138.
- ^ Woods, A. S.; Ugarov, M.; Egan, T.; Koomen, J.; Gillig, K. J.; Fuhrer, K.; Gonin, M.; Schultz, J. A., Lipid/peptide/nucleotide separation with MALDI-ion mobility-TOF MS. Analytical Chemistry 2004, 76 (8), 2187-2195.
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