AL-38022A

AL-38022A
Systematic (IUPAC) name
	(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
ATC code	?
PubChem	CID 22496603
ChemSpider	26286943
Chemical data
Formula	C13H17N3O
Mol. mass	231.293 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C13H17N3O/c1-9(14)8-16-13-10(7-15-16)4-5-12-11(13)3-2-6-17-12/h4-5,7,9H,2-3,6,8,14H2,1H3/t9-/m0/s1; Key:FJRIVFVALIEIOY-VIFPVBQESA-N ;
Physical data
Melt. point	106–107 °C (223–225 °F)
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AL-38022A is an indazole derivative drug which is one of a range of similar drugs developed for scientific research and with some possible clinical applications. It acts as a potent and selective agonist for the 5-HT₂ family of serotonin receptors, with highest binding affinity for the 5-HT_2C subtype and around 4x less affinity for 5-HT_2A and 5-HT_2B. In drug discrimination tests on animals, it fully substituted for both DOM and 5-MeO-DMT.^[1]

[edit] See also

[edit] References

^ May, JA; Sharif, NA; Chen, HH; Liao, JC; Kelly, CR; Glennon, RA; Young, R; Li, JX et al. (2009). "Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A (S)-2-(8,9-dihydro-7H-pyrano2,3-gindazol-1-yl)-1-methylethylamine". Pharmacology, biochemistry, and behavior 91 (3): 307–14. doi:10.1016/j.pbb.2008.07.015. PMID 18718483.

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[0] May, JA; Sharif, NA; Chen, HH; Liao, JC; Kelly, CR; Glennon, RA; Young, R; Li, JX et al. (2009). "Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A (S)-2-(8,9-dihydro-7H-pyrano2,3-gindazol-1-yl)-1-methylethylamine". Pharmacology, biochemistry, and behavior 91 (3): 307–14. doi:10.1016/j.pbb.2008.07.015. PMID 18718483.

[1]

Dec	JAN	Feb
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2011	2012	2013

AL-38022A

[edit] See also

[edit] References

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