Mepyramine
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| Systematic (IUPAC) name | |
| N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| MedlinePlus | a606008 |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 91-84-9  59-33-6 (maleate) |
| ATC code | R06AC01 D04AA02 |
| PubChem | CID 4992 |
| IUPHAR ligand | 1220 |
| DrugBank | DB06691 |
| ChemSpider | 4818 |
| UNII | HPE317O9TL |
| KEGG | D08183 |
| ChEBI | CHEBI:6762  |
| ChEMBL | CHEMBL511 |
| Synonyms | N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine |
| Chemical data | |
| Formula | C17H23N3O |
| Mol. mass | 285.38 g/mol |
| SMILES | eMolecules & PubChem |
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Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor.[1] However, it rapidly permeates the brain often causing drowsiness. It also has anticholinergic properties. It is used in over-the-counter combination products to treat the common cold and menstrual symptoms.[2] It is also the active ingredient of the topical antihistamine creams Anthisan and Neoantergan, sold for the treatment of insect bites, stings and nettle rash.
[edit] References
- ^ Parsons, M. E. and Ganellin, C. R. (2006). "Histamine and its receptors". British Journal of Pharmacology 147 (S1): S127–S135. doi:10.1038/sj.bjp.0706440. PMC 1760721. PMID 16402096. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1760721.
- ^ Active Ingredients for Midol Complete
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