Viqualine

Viqualine
Systematic (IUPAC) name
	4-[3-[(3R,4R)-3-ethenylpiperidin-4-yl]propyl]-6-methoxyquinoline
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	72714-74-0
ATC code	?
PubChem	CID 51669
UNII	1Y3A5E2L1J
Chemical data
Formula	C20H26N2O
Mol. mass	310.432 g/mol
SMILES	eMolecules & PubChem
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Viqualine (PK-5078) is a psychoactive drug and research chemical of the quinoline chemical class that possesses antidepressant and anxiolytic properties.^[1] It acts as a selective serotonin releasing agent (SSRA).^[2] It has mainly been researched as a potential treatment for alcoholism.^[3]^[4]

[edit] References

^ Faravelli C, Albanesi G, Sessarego A (1988). "Viqualine in resistant depression: a double-blind, placebo-controlled trial". Neuropsychobiology 20 (2): 78–81. doi:10.1159/000118477. PMID 3075725.
^ Le Fur G, Imbault F, Mitrani N, Marquis F, Renault C, Dubroeucq MC, Gueremy C, Uzan A (February 1984). "The 5-hydroxytryptamine-releasing properties of two epimer quinoline derivatives". Neuropharmacology 23 (2A): 169–73. doi:10.1016/S0028-3908(84)80010-6. PMID 6717757.
^ Naranjo CA, Sellers EM (1989). "Serotonin uptake inhibitors attenuate ethanol intake in problem drinkers". Recent Developments in Alcoholism : an Official Publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism 7: 255–66. PMID 2522667.
^ Naranjo CA, Sullivan JT, Kadlec KE, Woodley-Remus DV, Kennedy G, Sellers EM (September 1989). "Differential effects of viqualine on alcohol intake and other consummatory behaviors". Clinical Pharmacology and Therapeutics 46 (3): 301–9. doi:10.1038/clpt.1989.142. PMID 2673621.

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