Cyclorphan
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|---|---|
| Systematic (IUPAC) name | |
| 3-hydroxy-N-cyclopropylmethylmorphinan | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 4163-15-9 |
| ATC code | ? |
| PubChem | CID 5359966 |
| ChemSpider | 4514407 |
| ChEMBL | CHEMBL49269 |
| Chemical data | |
| Formula | C20H27NO |
| Mol. mass | 297.434 g/mol |
| SMILES | eMolecules & PubChem |
Cyclorphan is a hallucinogenic opioid mixed agonist-antagonist related to levorphanol discovered in the late 1960s. It is not marketed as an analgesic because of side effects related to its impact on the kappa opioid receptor,[1][2] but has found some use as a research chemical on and off since its discovery.
[edit] References
- ^ Herling S, Hein DW, Nemeth MA, Valentino RJ, Woods JH. (Jan 1982). "Discriminative stimulus, antagonist, and rate-decreasing effects of cyclorphan: multiple modes of action". Life Sciences 30 (4): 331–41. doi:10.1016/0024-3205(82)90569-0. PMID 6122153.
- ^ Bertalmio AJ, Woods JH. (1992). "Discriminative stimulus effects of cyclorphan: selective antagonism with naltrexone". Psychopharmacology (Berlin) 106 (2): 189–94. PMID 1347952.
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