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KEGG   DRUG: D08216Help
Entry
D08216                      Drug                                   
Name
Mianserin (INN);
Tolvon (TN)
Formula
C18H20N2
Exact mass
264.1626
Mol weight
264.3648
Structure
Mol fileKCF fileDB searchJmolKegDraw
Target
5-HT1-receptor antagonist [HSA:3350 3351 3352 3354 3355] [KO:K04153];
5-HT2-receptor antagonist [HSA:3356 3357 3358] [KO:K04157];
alpha2-adrenergic receptor antagonist [HSA:150 151 152] [KO:K04138 K04139 K04140];
alpha1-adrenergic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04540  Gap junction
hsa04970  Salivary secretion  		 
Metabolism
Enzyme: CYP3A4 [HSA:1576], CYP1A2 [HSA:1544], CYP2C19 [HSA:1557], CYP2D6 [HSA:1565]
Interaction
Drug interaction
Activity
Antidepressant, tetracyclic
Remark
ATC code: 
BRITE hierarchy
Comment
tetracyclic antidepressants
Structure map
map07027  Antidepressants
Other DBs
CAS: 
24219-97-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

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