Amedalin
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| Systematic (IUPAC) name | |
| 3-methyl-3-[3-(methylamino)propyl]-1-phenyl-1,3-dihydro-2H-indol-2-one | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 22136-26-1 22232-73-1 (HCl) |
| ATC code | None |
| PubChem | CID 31075 |
| ChemSpider | 28832  |
| UNII | 2OWK6X9N16 |
| Chemical data | |
| Formula | C19H22N2O |
| Mol. mass | 294.39 g/mol |
| SMILES | eMolecules & PubChem |
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Amedalin (UK-3540-1) is an antidepressant which was synthesized in the early 1970s, but was never marketed.[1][2] It is a selective norepinephrine reuptake inhibitor, with no significant effects on the reuptake of serotonin and dopamine, and no antihistamine or anticholinergic properties.[2] [3]
[edit] See also
[edit] References
- ^ David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9. http://books.google.com/books?id=DeX7jgInYFMC&lpg=PA65&dq=amedalin&pg=PA65#v=onepage&q=amedalin&f=false.
- ^ a b Canas-Rodriquez A, Leeming PR (1972). "N-Phenyl-2-indolinones and N-phenylindolines - New class of antidepressant agents". Journal of Medicinal Chemistry 15 (7): 762–770. doi:10.1021/jm00277a017. http://pubs.acs.org/doi/abs/10.1021/jm00277a017.
- ^ Koe BK (December 1976). "Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain". Journal of Pharmacology and Experimental Therapeutics 199 (3): 649–661. http://jpet.aspetjournals.org/content/199/3/649.abstract.
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