Tetrindole

Tetrindole
Systematic (IUPAC) name
	2,3,3a,4,5,6-Hexahydro-8-cyclohexyl-1H-pyrazino[3,2,1-j,k]carbazole
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
ATC code	None
PubChem	CID 160020
ChemSpider	140675
Chemical data
Formula	C20H26N2
Mol. mass	294.43 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C20H26N2/c1-2-5-14(6-3-1)15-9-10-19-17(13-15)16-7-4-8-18-20(16)22(19)12-11-21-18/h9-10,13-14,18,21H,1-8,11-12H2 ; Key:AUXCHYJDVJZEPG-UHFFFAOYSA-N ;
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Tetrindole is a tetracyclic antidepressant that functions by inhibiting monoamine oxidase A.^[1] Tetrindole has also been shown to reduce post-stressor tachycardia in rats.^[2]

References

^ Medvedev, Alexei E.; Alexandra A. Kirkel, Natalia S. Kamyshanskaya, Tatyana A. Moskvitina, Ludmila N. Axenova, Vladimir Z. Gorkin, Natalia I. Andreeva, Svetlana M. Golovina and Mikhail D. Mashkovsky (20). "Monoamine oxidase inhibition by novel antidepressant tetrindole". Biochemical Pharmacology 47 (2): 303–308. doi:10.1016/0006-2952(94)90021-3. PMID 8304974. http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T4P-4789T9N-6W&_user=10&_coverDate=01%2F20%2F1994&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=885bd8d3f1624a1839d98ecec7f6427d&searchtype=a. Retrieved 7 February 2011.
^ Korshunov, VA; Murashev AN, Ivashev MN, Dugin SF, Medvedev OS (September–October 2000). "Comparative study of hemodynamic effects of antidepressants (tetrindole and desipramine) during immobilization stress in hypertensive rats". Eksperimental'naia i klinicheskaia farmakologiia 63 (5): 18–20. PMID 11109518.

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