Morazone
| Systematic (IUPAC) name | |
|---|---|
| 1,5-dimethyl-4-[(3-methyl-2-phenylmorpholin-4-yl)methyl]-2-phenyl-1,2-dihydro-3H-pyrazol-3-one | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ℞ Prescription only |
| Routes | Oral, SC, IM[1] |
| Identifiers | |
| CAS number | 6536-18-1 |
| ATC code | None |
| PubChem | CID 39609 |
| ChemSpider | 36216 |
| UNII | 870Q5BL2FN |
| Chemical data | |
| Formula | C23H27N3O2 |
| Mol. mass | 377.48 g/mol |
| SMILES | eMolecules & PubChem |
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Morazone (Novartrina, Orsimon, Rosimon-Neu, Tarcuzate) is a non-steroidal anti-inflammatory drug (NSAID) originally developed by the German pharmaceutical company Ravensberg in the 1950s.[2] Morazone is used as an analgesic.[1][3] It produces phenmetrazine as a major metabolite and has been reported to have been abused as a recreational drug in the past.[4][5][6][7]
[edit] See also
[edit] References
- ^ a b Seyffart, G. (1991). Drug dosage in renal insufficiency. Boston: Kluwer Academic Publishers. pp. 399. ISBN 0-7923-0964-2. http://books.google.com/books?id=FubgMz6aOWAC&lpg=PA399&dq=morazone&pg=PA399#v=onepage&q=&f=false.
- ^ US patent 2943022, Siemer, H. & Doppstadt, A., "Substituted l-phenyl-2,3-dimethyl-4-morpholino methyl pyrazolone-(S) Compounds and Process of making same", issued 1960-06-28, assigned to Ravensberg
- ^ Dictionary of organic compounds. London: Chapman & Hall. 1996. p. 4659. ISBN 0-412-54090-8. http://books.google.com/books?id=r7z8W69GcoMC&lpg=PA4659&pg=PA4659#v=onepage&q=&f=false.
- ^ Bohn, G.; Rücker, G.; Kröger, H. (1976). "Investigations of the decomposition and detection of morazone by thin-layer- and gas-liquid-chromatography". Archives of toxicology 35 (3): 213–220. PMID 989292.
- ^ Neugebauer, M. (1984). "Some new urinary metabolites of famprofazone and morazone in man". Journal of pharmaceutical and biomedical analysis 2 (1): 53–60. PMID 16867765.
- ^ Kingreen, J. C.; Breger, G. (1984). "Pellagra in morazone abuse". Zeitschrift für Hautkrankheiten 59 (9): 573–577. PMID 6145264.
- ^ Daunderer, M.; Janzen, W. (1972). "Rosimon-NEU--a non-prescription analgesic on the adolescent drug scene". Beiträge zur gerichtlichen Medizin 29: 138–143. PMID 5081964.
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