Aceclidine
From Wikipedia, the free encyclopedia
| Systematic (IUPAC) name | |
|---|---|
| 1-azabicyclo[2.2.2]oct-3-yl acetate | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ℞ Prescription only |
| Routes | Ocular |
| Identifiers | |
| CAS number | 827-61-2 6109-70-2 (HCl) |
| ATC code | S01EB08 |
| PubChem | CID 1979 |
| ChemSpider | 1902 |
| UNII | 0578K3ELIO |
| KEGG | D02750 |
| ChEMBL | CHEMBL20835 |
| Chemical data | |
| Formula | C9H15NO2 |
| Mol. mass | 169.221 g/mol |
| SMILES | eMolecules & PubChem |
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Aceclidine (Glaucostat, Glaunorm, Glaudin) is a parasympathomimetic miotic agent used in the treatment of narrow angle glaucoma. It decreases intraocular pressure.
Contents |
[edit] Adverse effects
Side effects of aceclidine include increased salivation and bradycardia (in excessive doses).
[edit] Mechanism of action
Aceclidine acts as a muscarinic acetylcholine receptor agonist.[1]
[edit] See also
[edit] References
- ^ Shannon HE, Hart JC, Bymaster FP, et al. (August 1999). "Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats". J. Pharmacol. Exp. Ther. 290 (2): 901–7. PMID 10411607. http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=10411607.
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