Prolintane
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| Systematic (IUPAC) name | |
| 1-(1-benzylbutyl)pyrrolidine | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 493-92-5 |
| ATC code | N06BX14 |
| PubChem | CID 14592 |
| ChemSpider | 13930  |
| UNII | EM4YZW677H |
| Chemical data | |
| Formula | C15H23N |
| Mol. mass | 217.35 g/mol |
| SMILES | eMolecules & PubChem |
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Prolintane (Catovit) is a stimulant[1] of norepinephrine-dopamine reuptake inhibitors developed in the 1950s[2] which is closely related in chemical structure to other drugs such as pyrovalerone and MDPV, and with a similar mechanism of action. It is a mild stimulant with a very good safety profile.[3] The good safety profile of this drug makes it suitable for use in elderly people to increase motivation and counteract the effects of senile dementia and age-related cognitive decline.[4] It is mainly used in European countries. Anecdotally cases of prolintane abuse have been reported.[5][6][7]
See also
- α-PVP
- Methylenedioxypyrovalerone (MDPV)
- Pyrovalerone (Centroton, Thymergix)
References
- ^ Hollister, L. E.; Gillespie, H. K. (1970). "A new stimulant, prolintane hydrochloride, compared with dextroamphetamine in fatigued volunteers". The Journal of clinical pharmacology and the journal of new drugs 10 (2): 103–109. PMID 4392006.
- ^ GB Patent 807835
- ^ Nicholson, A. N.; Stone, B. M.; Jones, M. M. (1980). "Wakefullness and reduced rapid eye movement sleep: Studies with prolintane and pemoline". British journal of clinical pharmacology 10 (5): 465–472. PMC 1430138. PMID 7437258.
- ^ Kuitunen, T.; Kärkkäinen, S.; Ylitalo, P. (1984). "Comparison of the acute physical and mental effects of ephedrine, fenfluramine, phentermine and prolintane". Methods and findings in experimental and clinical pharmacology 6 (5): 265–270. PMID 6471970.
- ^ Payá, B.; Guisado, J. A.; Vaz, F. J.; Crespo-Facorro, B. (2002). "Visual Hallucinations Induced by the Combination of Prolintane and Diphenhydramine". Pharmacopsychiatry 35 (1): 24–25. doi:10.1055/s-2002-19829. PMID 11819155.
- ^ Gaulier, J. M.; Canal, M.; Pradeille, J. L.; Marquet, P.; Lachâtre, G. (2002). "New drugs at "rave parties": Ketamine and prolintane". Acta clinica Belgica. Supplementum (1): 41–46. PMID 11974443.
- ^ Kyle, PB; Daley, WP (2007). "Domestic abuse of the European rave drug prolintane". Journal of analytical toxicology 31 (7): 415–8. PMID 17725890.
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