Captodiame

Captodiame
Systematic (IUPAC) name
	2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethylethanamine
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral
Pharmacokinetic data
Excretion	Renal
Identifiers
CAS number	486-17-9
ATC code	N05BB02
PubChem	CID 10240
ChemSpider	9823
UNII	H93K9455DD
KEGG	D07316
Chemical data
Formula	C21H29NS2
Mol. mass	359.594 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C21H29NS2/c1-4-5-16-23-20-13-11-19(12-14-20)21(24-17-15-22(2)3)18-9-7-6-8-10-18/h6-14,21H,4-5,15-17H2,1-3H3 ; Key:IZLPZXSZLLELBJ-UHFFFAOYSA-N ;
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Captodiame (INN), also known as captodiamine, is an antihistamine sold under the trade names Covatine, Covatix, and Suvren which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine.^[1]

A 2004 study suggested captodiame may be helpful in preventing benzodiazepine withdrawal syndrome in people discontinuing benzodiazepine treatment.^[1]

[edit] See also

^ ^a ^b Mercier-Guyon C, Chabannes JP, Saviuc P (2004). "The role of captodiamine in the withdrawal from long-term benzodiazepine treatment". Curr Med Res Opin 20 (9): 1347–55. doi:10.1185/030079904125004457. PMID 15383182. Free full text with registration

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