Carbendazim
| Carbendazim[1] | |
|---|---|
 |
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Methyl 1H-benzimidazol-2-ylcarbamate |
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Other names
Mercarzole |
|
| Identifiers | |
| CAS number | 10605-21-7  |
| PubChem | 25429 |
| ChemSpider | 23741 |
| UNII | H75J14AA89 |
| KEGG | C10897 |
| ChEMBL | CHEMBL70971 |
| RTECS number | DD6500000 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C9H9N3O2 |
| Molar mass | 191.19 g mol−1 |
| Appearance | Light gray powder |
| Melting point |
302-307 °C (decomposes) |
| Solubility in water | 8 mg/L |
| Acidity (pKa) | 4.48 |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
|
| Infobox references |
Carbendazim is a widely used broad-spectrum benzimidazole fungicide and a metabolite of benomyl.
The fungicide is used to control plant diseases in cereals and fruit, including citrus, bananas, strawberries, pineapples, and pome.[2] It is also controversially used in Queensland, Australia on macadamia plantations.[3]A 4.7% solution of carbendazim hydrochloride is sold as Eertavas and marketed as a treatment for Dutch elm disease.
Studies have found that high doses of carbendazim cause infertility and destroy the testicles of laboratory animals.[4][5] Carbendazim was included in a biocide ban proposed by the Swedish Chemicals Agency [6] and approved by the European Parliament on January 13, 2009.[7]
[edit] References
- ^ Merck Index, 11th Edition, 1794.
- ^ Wight, Andrew (14 January 2009). "Two-headed fish mystery deepens". Stock & Land. Archived from the original on 11 January 2012. http://sl.farmonline.com.au/news/nationalrural/agribusiness-and-general/general/twoheaded-fish-mystery-deepens/1406893.aspx?storypage=0.
- ^ Marissa Calligeros (2009-02-02). "Fungicide maker in birth defect storm". Sydney Morning Herald. http://www.smh.com.au/news/environment/fungicide-maker-in-birth-defect-storm/2009/02/02/1233423096718.html. Retrieved 2010-03-21.
- ^ Aire, TA (2005 Aug). "Short-term effects of carbendazim on the gross and microscopic features of the testes of Japanese quails (Coturnix coturnix japonica).". Anatomy and embryology 210 (1): 43-9. PMID 16034611.
- ^ "Carbendazim use banned on fruit crops". ABC. 5 February 2010. http://www.abc.net.au/rural/news/content/201002/s2811428.htm.
- ^ "Interpretation of criteria for approval of active substances in the proposed EU plant protection regulation". Swedish Chemicals Agency (KemI). 2008-09-23. http://www.kemi.se/templates/News____5415.aspx. Retrieved 2009-01-14.
- ^ "MEPs approve pesticides legislation". 2009-01-13. http://www.europarl.europa.eu/news/expert/infopress_page/066-45937-012-01-03-911-20090112IPR45936-12-01-2009-2009-false/default_en.htm. Retrieved 2009-01-14.
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